A high-level inquiry into the Intergovernmental Panel on Climate Change found there was
Climate Change Lies Exposed
Little Exposure To BPA Turns Offspring Into Genetic Mutants
A recent study published online in the journal Biology of Reproduction further reveals the disruptive nature of bisphenol A (BPA) in gene expression. According to the data, pregnant mice exposed to BPA experience significant genetic changes in their fetal ovaries, indicating that the next generation of their offspring will likely be born with serious genetic defects.
Dr. Patricia A. Hunt and her colleagues at Washington State University (WSU) in Pullman, Wash., exposed female mice to levels of BPA roughly equivalent to the levels humans are exposed to on a regular basis. The team discovered that in as little as 12 hours after exposure, egg production in exposed mice suffered reproductive damage. They believe exposure even altered the reproductive capacity of the mice’s grandchildren.
According to the study report, BPA exposure negatively affects mitosis, the process by which cells divide their nuclei chromosomes in order to reproduce into new cells. BPA also disrupts other normal cell cycle functions and DNA replication, which researchers say can potentially shorten the “reproductive lifespan” of females.
What makes BPA particularly dangerous is the fact that very low levels of exposure to it can cause significant harm. According to reports, there have already been more than 200 studies conducted about BPA’s dangers, many of which implicate the chemical as being highly dangerous even at extremely low levels.
One such study that appeared in the journal Reproductive Toxicology found that newborn animals exposed to BPA experience uterine damage.
“The researchers indicated that such damage is a possible predictor of reproductive diseases in women, including fibroids, endometriosis, cystic ovaries and cancers,” explains Andreas Moritz in his book Timeless Secrets of Health & Rejuvenation: Unleash The Natural Healing Power That Lies Dormant Within You.
Editor’s Note: NaturalNews is strongly against the use of all forms of animal testing. We fully support the implementation of humane medical experimentation that promotes the health and well-being of all living creatures.
Anticonvulsant Drug Makes People Suicidal
Popular anti-seizure drugs may seriously increase a patient’s risk of suicide and violent death, according to a study conducted by researchers from Brigham and Women’s Hospital and Harvard Medical School, and published in the Journal of the American Medical Association.
The drugs, known as anticonvulsants, were initially designed for the treatment of epilepsy but are now widely prescribed “off-label” for conditions such as bipolar disorder, migraine headaches and pain.
“We all know the range of uses of these medications is very, very wide,” researcher Elisabetta Patorno said.
The researchers examined the prescription and medical records of more than 300,000 people above the age of 14 who had been prescribed an anticonvulsant for the first time between July 2001 and December 2006.
All of the drugs, they found, significantly increased a patient’s risk of attempted or successful suicide, as well as violent death by other causes. During the course of the study, there were 801 attempted suicides, 26 successful suicides and 41 violent deaths.
“We found increased risk for suicidal acts beginning within the first 14 days after treatment initiation, opening the possibility that anticonvulsant medications could induce behavioral effects prior to the achievement of their full therapeutic effectiveness,” the researchers wrote.
Based on prior studies, the FDA ruled in 2008 that all anticonvulsants must carry labels warning that they double the risk of suicidal thoughts and actions. These older studies had not been able to determine if any drugs posed higher risks than others, however.
In the current study, researchers compared the rates of suicides and violent deaths among users of topiramate (sold generically and also marketed as Topamax), gabapentin (marketed as Neurontin), lamotrigine (marketed as Lamictal), oxcarbazepine (marketed as Trileptal), tiagabine (marketed as Gabitril) and valproate (marketed as Depakine and Epilim). They found that the risk was lowest in topiramate, and roughly equal in the five other drugs.
Toothpaste, Soap, Make-Up Can Harm You
Over the past several months, your bathroom has become the site of a major controversy. In fact, the controversy has been heating up for a while (Environmental Working Group’s Cosmetic Safety Database dates back to 2004), but recently, stories of dangerous ingredients in common personal care products like soap, toothpaste and lipstick have become even more common in the media. They’re even the subject of a bill in Congress, The Safe Cosmetics Act of 2010. The inadequate regulation and dubious safety of cosmetics spurred Annie Leonard, famous for making The Story of Stuff, to come out with a new video last month, The Story of Cosmetics.
Numerous chemicals that are legally used in personal care products are untested, inadequately tested, or even proven harmful, but few are as widely used and as unnecessary as the endocrine disrupting chemicals triclosan (an ingredient in 75 percent of liquid hand soaps) and triclocarban (most commonly found in deodorant bar soaps). Scientists have recently found a number of new reasons why these chemicals should not be used in consumer products. In late July, the Natural Resources Defense Council (NRDC) brought a lawsuit against the Food and Drug Administration (FDA), calling on the FDA to ban triclosan and triclocarban from soaps and body washes.
Together, triclosan and triclocarban are widely used in antibacterial soaps, body washes, deodorants, lip glosses, dog shampoos, shave gels, and even toothpastes. They are found in brands as familiar as Colgate, Dial, Lever 2000, and Vaseline. Although they have been used for several decades for their antibacterial and antifungal properties, studies and even the FDA recognize that they are no more effective at preventing disease than regular soap and water. In other words, they serve two real purposes: allowing companies to market personal care products as “antibacterial,” and contaminating the waste stream (and, ultimately, the environment).
In 2009, the EPA tested 84 sewage sludge samples from around the U.S. and found triclocarban in every sample and triclosan in 79 samples. Research published in 2007 also showed that triclocarban appears more frequently and in higher concentrations downstream of wastewater treatment plants, compared to upstream. That implies that these chemicals are not just entering wastewater treatment plants — they are also exiting the plants in sewage sludge and effluent. Triclocarban is rather persistent and does not break down for over a decade. Triclosan, on the other hand, does break down — into dioxins. And, alarmingly, the Centers for Disease Control (CDC) published data in July showing that the level of triclosan in Americans increased, on average, by more than 40 percent in a two-year period (from 2003-’04 to 2005-’06).
So what are the effects of these chemicals we are putting into our environment and even into our own bodies? Setting aside the dioxins — a class of chemicals that are well-documented carcinogens — both triclosan and triclocarban appear to be endocrine disruptors. Scientists say that triclocarban appears unique in that it doesn’t show endocrine activity by itself and instead enhances the expression of other hormones, such as androgens (male hormones like testosterone), estrogens and cortisol. In animal studies, triclosan also affects male and female sex hormones. Additionally, it interferes with thyroid hormone.
Obviously, a major route of exposure to triclosan and triclocarban are through personal care products. Their use in soaps can result in absorption through the skin into the bloodstream, and those who use toothpastes with triclosan are putting the chemical directly into their mouths, where it can remain present in saliva for hours. Additionally, a study published last month found that soybean plants in soil contaminated with triclosan and triclocarban uptake both chemicals into their roots, leaves and beans. This implies that crops fertilized with sewage sludge or irrigated with effluent from wastewater treatment plants, both of which are often contaminated with these chemicals, would result in food contaminated with triclosan and triclocarban. (It should also be noted that, since sewage sludge is sold in composts and fertilizer for home gardeners, proof that plants uptake a harmful chemical should not be the standard used to determine that chemical’s safety in sewage sludge. Home gardeners and their children would be exposed to any chemical in sludge sold commercially as they garden or play in the soil.)
NRDC cites both the recent news from the CDC about the increase in triclosan found in the bodies of Americans (or, more specifically, in their urine) and the study finding that soybeans uptake triclosan and triclocarban into the edible portions of the plant in its press release announcing its lawsuit. NRDC’s senior scientist Dr. Sarah Janssen said, “With no proven benefit and many red flags raised for harmful health impacts, the use of these so-called anti-microbials is an unnecessary and stupid use of toxic chemicals.”
On its Web site, the FDA says that triclosan “is not currently known to be hazardous to humans,” also providing the caveat that “several scientific studies have come out since the last time FDA reviewed this ingredient that merit further review.” Of course, that is not the same as saying that triclosan is definitely safe. The FDA continues by raising the question of whether triclosan “contributes to making bacteria resistant to antibiotics” and concluding that, while triclosan may provide some benefit in toothpaste by preventing gingivitis, there is no other evidence that it provides any other benefits to health. The FDA has no similar page on triclocarban.
Currently, both the FDA and the EPA are taking a fresh look at triclosan, at the urging of Rep. Edward Markey, D-Mass. In April, Markey told the Washington Post, “The proliferation of triclosan in everyday consumer products is so enormous, it is literally in almost every type of product — most soaps, toothpaste, cosmetics, clothes and toys. It’s in our drinking water, it’s in our rivers and as a result, it’s in our bodies … I don’t think a lot of additional data has to be collected in order to make the simple decisions about children’s toys and soaps that people use. It clearly is something that creates a danger.”
Markey was also one of three members of Congress to introduce the Safe Cosmetics Act, along with Rep. Jan Schakowsky, D-Illinois, and Rep. Tammy Baldwin, D-Wisc. The bill aims to phase out ingredients linked to cancer, birth defects and developmental harm that are currently used in cosmetics, improve labeling requirements for cosmetics, and to establish a list of cosmetic ingredients that are known to be safe. This would be an improvement to cosmetic safety in so many ways, since it’s currently voluntary for a manufacturer to ensure the products it sells don’t contain known carcinogens, neurotoxins, endocrine disruptors, and other harmful chemicals.
In fact, many chemicals used in cosmetics just aren’t tested for safety in the first place. The FDA leaves safety to the industry, which in turn sets voluntary standards for cosmetics companies and tests less than 20 percent of ingredients used in cosmetics for safety. Since 1938, the U.S. has banned only eight ingredients out of the 12,000 used in personal care products. In contrast, the E.U. bans over 1,300. That not only reinforces the fact that Americans are unnecessarily and legally exposed to harmful ingredients in their soaps, shampoos and lotions; it also shows that any company selling products in both the U.S. and Europe already knows how to produce its products free of the over 1,300 ingredients banned in the E.U. Surely it wouldn’t be unreasonable to ask them to uphold the same safety standard for their U.S. market.
Would adopting Europe’s standards or passing the Safe Cosmetics Act remove triclosan and triclocarban from our household products? Perhaps not. The list of chemicals banned in Europe includes heavy metals, phthalates, polycyclic aromatic hydrocarbons, and even pharmaceuticals. Some of these chemicals aren’t used in U.S. personal care products anyway. But some are. Take, for example, dibutyl phthalate. You can find that one in any number of Sally Hansen or Cover Girl nail polishes. However, the list of chemicals banned in Europe does not include triclosan or triclocarban. (Nor does it include other chemicals commonly used in personal care products that are potentially harmful, like sodium lauryl sulfate or parabens.) And recall that the FDA, pending its review of triclosan’s safety, continues to allow its use and warn of no human safety hazards (even as it recognizes that “animal studies have shown that triclosan alters hormone regulation.”
In other words, it seems that, while the passage of the Safe Cosmetics Act would improve the safety of personal care products in the U.S., it wouldn’t be a silver bullet. Consumer advocates would need to remain vigilant as the FDA formulates its lists of chemicals banned, restricted, and permitted in cosmetics. And, even if NRDC is successful in its lawsuit to ban triclosan and triclocarban, Americans will still be exposed to triclocarban, triclosan and their breakdown products (including dioxins) for years to come.
Vitamin D Prevents Cancer, Autoimmune Diseases
A new study out of Oxford University pinpoints vitamin D deficiency as a culprit in serious illnesses like cancer and autoimmune disorders. According to the report, which was recently published online in the journal Genome Research, genetic receptors throughout the body need adequate vitamin D levels to prevent these and other serious illnesses from developing.
Multiple sclerosis, diabetes, rheumatoid arthritis, Chron’s disease, leukemia — these and many more diseases are often caused by a lack of vitamin D. Your genes literally have receptors that need vitamin D in order to properly express themselves. If there is not enough of the vitamin, serious illness is prone to develop.
The Oxford team made specific observations about the importance of vitamin D in the genome regions associated with autoimmune diseases and cancer, noting that the nutrient is absolutely vital in helping to prevent these diseases from forming.
“Considerations of vitamin D supplementation as a preventative measure for these diseases are strongly warranted,” expressed Sreeram Ramagopalan, author of the study.
However, current recommendations for vitamin D intake are unacceptably low, and many nations are considering updating their guidelines. The U.S. Institute of Medicine, for example, recommends getting a mere 200 to 600 international units (IU) of vitamin D a day, an amount far too low to have much therapeutic effect.
Since summer sun exposure creates about 20,000 IU of vitamin D in the skin in just 15 minutes, supplementation with at least 5,000 to 10,000 IU of vitamin D daily, particularly during the winter, is preferable. Healthy blood levels of vitamin D are somewhere between 50 and 80 nanograms per milliliter (ng/ml), so many natural health professionals recommend having a “25 OH Vitamin D” blood test performed to check these levels.
Prescription Painkillers Now Gateway Drugs To Hard Drug Use
Shocking new research out of the University of Buffalo has revealed that popular prescription opioid medications are causing people to become addicted to street drugs. Once addicted, nearly half of patients prescribed opioid pain pills end up transitioning to street drugs like heroin because these drugs are generally cheaper and can be easier to obtain.
Of 75 patients hospitalized at Erie County Medical Center in Buffalo, New York, for detoxification, over 41 percent told their doctors that they became addicted to street drugs after being prescribed opioid medications — like methadone, oxycodone and fentanyl — by their doctors. Ninety-two percent of all patients in the program indicated that these prescription opioids actually led them to street drugs.
“This information suggests that there is a progressive nature to opioid use, and that prescription opioids can be the gateway to illicit drug addition,” explained Richard Blondell, M.D., professor of family medicine and senior author of the study, in a press release.
The majority of patients in the detoxification program first began taking prescription opioids for pain following injuries or surgeries. In other words, the legitimate use of prescription drugs prescribed to patients by their doctors is a leading cause of substance abuse.
To make matters worse, most doctors fail to even ask patients if they have ever had a substance abuse problem prior to writing them an opioid prescription. So many doctors are directly responsible for helping to induce drug addiction through their neglect and carelessness in monitoring patients.
Additionally, a 2009 study found that the majority of patients who die from opioid overdoses did so due to prescription opioids anyway, indicating that even if patients do not transition to street drugs, their health is still at risk from legal opioids.
First Gene Link To Common Migraine
Gene detectives on Sunday announced they had found the first inherited link to common types of migraine, a finding that boosts hopes for new drugs to curb this painful and costly disorder.
Scientists from 40 medical centres pored over the genetic profiles of more than 50,000 people, comparing those who suffered badly from migraines with others who were otherwise healthy.
What came up in the net was a tiny but telltale variant of DNA that boosts the risk of getting migraines by around fifth.
“This is the first time we have been able to peer into the genomes of many thousands of people and find genetic clues to understand common migraine,” said Aarno Palotie, head of the International Headache Genetics Consortium at Britain’s Wellcome Trust Sanger Institute, which led the study.
Previous research has found links for some extreme, but mercifully rare, forms of migraine, but this is the first to pinpoint an association for common types of the disease.
The tiny genetic variant, or allele, is called rs1835740.
Lying on Chromosome 8 between two genes, PGCP and MTDH/AEG-1, it allows a messenger chemical called glutamate to accumulate in junctions between brain cells, and this unleashes the migraine, the scientists believe.
If so, drug engineers have a tempting target in preventing glutamate buildup, they hope.
The paper, published online in the journal Nature Genetics, cited figures that migraine affects 17 percent of European women and eight percent of men.
The UN’s World Health Organisation (WHO) ranks migraine in the top 20 diseases in terms of “years lived with disability,” a benchmark of handicap. A US estimate put migraine’s economic cost on a par with diabetes.
The study first compared the genome of more than 3,000 migraine sufferers in Finland, Germany and the Netherlands against that of some 10,000 non-sufferers.
These results were then compared in a second phase with the genomes of a second batch, comprising 3,000 migraine patients and more than 40,000 otherwise healthy people.
The study found rs1835740 to be one of several connecting genetic cogs in regulating glutamate levels.
The allele alters the MTDH/AEG-1 gene, which in turn affects a gene called EAA2.
The EAAT2 gene controls a protein that is responsible for clearing glutamate from the brain synapses. This protein has previously been linked with epilepsy, schizophrenia and various mood and anxiety disorders.
The authors say further work is needed to confirm the findings and see whether other genetic culprits abound.
Patients in the study were recruited mainly from specialist headache clinics, which means they are likely to represent only the more extreme end of those who suffer from common migraines, said Gisela Terwindt of Leiden University Medical Centre, the Netherlands.
“In the future, we should look at associations across the general population, including also people who are less severely affected,” she said.
Migraine is believed to occur when inflammatory chemicals are released around the nerves and blood vessels in the head, inducing pain that can be excruciating. It is sometimes accompanied by nausea and hyper-sensitivity to light and sound.
Common migraines fall into two categories — those with an “aura,” or shimmering circle seen by the sufferer, and those without.
Sufferers tend to be aged 35-45, although the frequency and duration of the attacks can very widely.
















